Best Liver Cleanse Supplements

The liver is one of the essential organs of the human body. A healthy liver is responsible for various body functions. It can help store amino acids and vitamins, produce liver enzymes, help maintain the digestive tract, and more.

The liver is also responsible for the detoxification of the body. If you don’t take care of your liver, it can lead to chronic liver disease. Liver diseases are directly linked to an increased number of free radicals.

Free radicals are nothing but free molecules. They can damage the liver and lead to hepatitis B, a chronic liver disease seen in people with poor liver detoxification and impaired liver function.

Alcohol consumption, smoking, poor diet, harmful chemicals, free radicals, viral infections, toxins, etc., can cause liver disorders such as liver inflammation, liver failure, and more.

Treating liver disorders or liver diseases can be a tedious and expensive case. A liver transplant may also be necessary in cases of chronic liver disease such as hepatitis B or chronic hepatitis. This is why it is essential to maintain liver health and care for your liver.

Luckily today, there are many liver supplements available on the market. These liver detox supplements are made to support liver health. They use ingredients such as artichoke leaf, milk thistle, zinc, dandelion root extract, and more. These ingredients are great for liver cells and tissue. They can also help with liver detoxification.

The Top Liver Supplements in 2022

Here’s a list of the best liver supplements we will take a look at today:

Oweli Liver Detox This liver detox formula comes from easy-to-consume tablets and uses Jujube fruit extract and zinc ingredients.
Organifi Liver Rest The Liver Reset is different from premium liver supplements as it aims to provide deep liver detox.
1MD LiverMD LiverMD by 1MD is a supplement for the liver that comes with the added goodness of vitamin E and ALA.
Live Conscious LiverWell This is a made in the USA and third-party testing-approved supplement rich in antioxidants.
Amy Myers MD Liver Support A capsule in a day of this health supplement can help you eliminate liver toxins.
Zenith Labs Zenith Detox This is a powerful detox solution that makes use of natural ingredients, backed by a doctor who helped to create it.
Gundry MD Complete Liver Support This is one of the most holistic and affordable products on our list today.
Advanced Bionutritionals Advanced Liver Support This is a high dosage supplement that requires you to take four capsules a day for liver benefits.
PureHealth Research Liver Health Formula This supplement aids in overall digestion crafted with the help of a naturopathic doctor.
ActivatedYou Morning Complete This powerful morning supplement comes with the goodness of prebiotics and probiotics.
VitaPost Liver Support Plus This supplement is excellent for your liver, using beet, zinc, artichoke extract, and more.
PhytAge Labs Urgent Liver 911 Backed by the reputation of PhytAge Labs and made with 23 ingredients, this is one of the best supplements for the liver.
Bonus Guide: The Non-alcoholic Fatty Liver Disease Solution A guidebook that can help people with Non-alcoholic Fatty Liver Disease

Our research and editorial team has picked the best liver detox supplements today to help you better care for your liver health. Keep reading to learn more about these liver detox supplements.

Out of the many liver supplements that claim to help with liver function and liver damage, we have only picked a handful. The liver health supplements included on this list benefit healthy liver function. They can also help reduce inflammation, thanks to their anti-inflammatory properties and natural detox formula that uses ingredients like artichoke leaf.

The liver cleanses and liver detox solutions on this list were picked out of hours of research. Consumers use these liver detox pills worldwide to help with liver detoxification and inflammation. Some of these liver supplements are also great for non-alcoholic fatty liver disease.

So, without further delay, here are the best liver detox supplements with natural and herbal ingredients that you can buy online now.

Oweli Liver Detox

Product Overview
Core Ingredients Zinc, milk thistle, beetroot, artichoke leaf, chicory root, yarrow, and more.
Servings Per Container 60
Side Effects No reported side effects.
Price $29.99

First, we have Oweli Liver Detox, one of the most prevalent liver detox supplements. This herbal supplement is made from powerful herbal ingredients such as artichoke leaf extract, milk thistle, dandelion root, Jujube fruit extract, zinc, and more.

Oweli Liver Detox supplement can promote liver health and detoxification in all individuals. From senior citizens to active young people and everyone in between, the Oweli Liver Detox supplement can help everyone.

According to their official website, this formula can support liver health and protect liver cells by promoting natural liver detox that can help you eliminate unwanted toxins such as environmental toxins.

This liver detox formula can also support healthy metabolism and is ideal for a modern lifestyle with a healthy diet and regular exercise. The Oweli Liver Detox can also help with oxidative stress, the immune system, and better blood flow.

Organifi Liver Reset

Product Overview
Core Ingredients Dandelion Root, Triphala, Artichoke Leaf Extract, Milk Thistle, etc
Servings Per Container 30
Side Effects No side effects reported
Price $27.95

Organifi Liver Reset is a powerful liver cleanse and detox formula backed by a money-back guarantee. It aims to provide a deep liver detox, which even premium liver detox supplements fail.

The liver cleanse formula of Organifi Liver Reset is made using powerful superfoods such as artichoke leaf extract, milk thistle extract, dandelion root, and Triphala. All these ingredients are known to support liver health and liver function.

Milk thistle is known for helping with liver health. It has anti-inflammatory properties. One of the significant reasons behind liver damage is free radicals. Milk thistle used in Organifi Liver Reset is said to help deal with these free radicals.

Similarly, the other herbal ingredients used here have antioxidant properties and can help with overall liver health. They can strengthen liver cells.

1MD LiverMD

Product Overview
Core Ingredients EVNolMax, Siliphos Bioavailable Silybin, Alpha Lipoic Acid (ALA), Zinc, etc.
Servings Per Container 30
Side Effects No side effects reported
Price $40.99

1MD LiverMD is a trendy liver supplement. It has an average of 4.5 out of 5 stars from over a thousand reviews on Amazon. It is also available on Walmart. If you are looking for extra discounts, this potent supplement for healthy liver function can also be bought via renewable subscriptions from their official website.

Its unique and high dosage blend of ingredients sets 1MD apart from other liver supplements and liver detox formulas. It contains zinc, alpha-lipoic acid (ALC), vitamin E, milk thistle extract, and more.

The milk thistle present in LiverMD is unlike the one found in other liver supplements as this is an extract of an enhanced variant of milk thistle. This is great for dealing with free radicals. Other ingredients such as Vitamin E are known for their antioxidant properties.

Alpha Lipoic Acid (ALC), a key ingredient in 1MD’s liver cleanse formula, is also great for weight loss and has overall health benefits. LiverMD uses all these ingredients in the perfect hormone manner for maximum health benefits.

Live Conscious LiverWell

Product Overview
Core Ingredients41 Altilix, Dandelion root, Triphala Churna, etc.
Servings Per Container 30
Side Effects No side effects reported
Price $25.99

Live Conscious LiverWell is another liver detox supplement primarily using milk thistle extract.

This liver health supplement has three primary ingredients: milk thistle, L-cysteine, and ALA. L-cysteine is one of the best amino acids, and just like ALA, it is an excellent source of antioxidants. This can be great for your blood flow.

As we have seen, milk thistle is used in many liver health supplements as it helps maintain good liver health and improve liver cells. And can reduce inflammation, among other benefits.

Besides providing you with a proven liver function, the LiverWell liver supplement promotes healthy metabolism. Better metabolism means easy and quick fat loss and weight loss.

LiverWell is wholly made in the USA and has undergone third-party testing. If you are looking for an affordable yet powerful and high-quality liver supplement to strengthen your liver, then the Live Conscious LiverWell is the right choice.

Amy Myers MD Liver Support

Product Overview
Core Ingredients Selenium, Milk Thistle Extract, ALA, and L-Glutathione
Servings Per Container 60
Side Effects No side effects were reported.
Price $38.22

The Amy Myers MD Liver Support formula is a great liver supplement and one of our favorites on this list of liver detox supplements. This supplement is made with high-quality ingredients that help to improve liver function and aid in liver detoxification.

Environmental toxins and other harmful toxins from alcohol consumption or smoking can harm the liver, and accumulating these toxins can also lead to liver disease. This is why liver detoxification is necessary.

This liver health supplement promotes detoxification, bile production, and more. The glutathione in this supplement can neutralize environmental toxins, which further helps your liver health. It also has ALA, which works as a free radical scavenger. It’s a powerful antioxidant that can effectively deal with free radicals.

This supplement also provides extra milk thistle support for liver cells and tissue. In addition to all these, it also has around 100mg of selenium per serving. Selenium is also rich in antioxidants.

Another thing that makes this supplement unique is that it is gluten-free, soy-free, non-dairy, non-GMO, egg-free, keto, and paleo-friendly, and free from added artificial sweeteners. It was made using GMP-compliant methods.

These factors make this one of our list’s best liver detox supplements.

Zenith Labs Zenith Detox

Product Overview
Core Ingredients Schisandra Berry extract, Setria Glutathione, L – Methionine, Silymarin Milk Thistle extract, etc.
Servings Per Container 30
Side Effects No side effects reported
Price $49.00

Zenith Labs Zenith Detox is a powerful liver detox formula. This is an all-in-one detox supplement that focuses on helping you get rid of toxins and free radicals. It supports anti-aging by eliminating free radicals with the help of a scientifically formulated blend of ingredients.

According to the official website of Zenith Labs, this liver detox supplement can not only provide proper liver function but also gives you more energy, helps deal with joint pain, counteracts aging by getting rid of free radicals, and improves physical stamina and confidence.

Zenith Detox contains many natural ingredients, essential vitamins, and minerals, all of which are made to help your liver.

Each pill of the Zenith Detox supplement contains artichoke leaf extract, milk thistle, dandelion root, beetroot extract, bupleurum root powder, choline bitartrate, and milk thistle seed extract, green tea leaf extract, broccoli sprout extract, and more.

It has minerals and vitamins like zinc, magnesium, vitamin B6, vitamin B12, and other essential nutrients such as folic acid, taurine, and more. These ingredients work together perfectly to help you deal with free radicals, liver issues, and aging.

Gundry MD Complete Liver Support

Product Overview
Core Ingredients Orange peel extract, Milk Thistle Extract, Dandelion, and more.
Servings Per Container 60
Side Effects No side effects reported
Price $19.48

Compared to the extensive list of key ingredients used by Zenith Labs, the Gundry MD Complete Liver Support formula contains three elements: orange peel extracts, milk thistle, and dandelion root.

The Gundry MD Complete Liver Support supplement comes in soft gel capsules, which are easy to consume. These capsules promote your normal liver function and help your immune system.

This liver support formula can also help with metabolism, making it easier for you to get rid of excess pounds. It can also be effective in getting rid of unwanted toxins from your liver. This can be effective in dealing with liver disease.

This is one of the most expensive and premium supplements on our list.

Advanced Bionutritionals Advanced Liver Support

Product Overview
Core Ingredients NAC, ALA, Milk Thistle Extract, Selenium, etc.
Servings Per Container 30
Side Effects No side effects reported
Price $49.95

Advanced Bionutritionals Advanced Liver Support contains a unique blend of selenium, licorice, milk thistle, ALA, Quercetin, Agaricus blazei, phosphatidylcholine, and more.

This liver support formula can support liver function. This is not just a liver supplement but a brain and liver health supplement. It can not only help with liver detox, and liver cleanses but also it can help with other overall liver health benefits.

Another benefit of this supplement is that it can aid in dealing with liver inflammation. An inflamed liver is nothing but the base cause of hepatitis b and other hepatitis.

PureHealth Research Liver Health Formula

Product Overview
Core Ingredients Ginger Powder, Organic Alfalfa Powder, Artichoke extract, Dandelion root extract, etc.
Servings Per Container 30
Side Effects No side effects were reported.
Price $62.10

The PureHealth Research Liver Health Formula is one of the best liver detox supplements on amazon. Not only does it help with liver function, but it has overall health benefits.

PureHealth Research Liver Health Formula is made from artichoke leaf extract, dandelion root, beetroot extract, milk thistle, turmeric, and alfalfa. All these ingredients are known for their health benefits. While milk thistle and artichoke leaf are excellent for proper liver health, turmeric is great for protecting against viral infections, which can turn into hepatitis b or c.

Another fantastic benefit of turmeric is that it contains the active component curcumin, which is excellent at getting rid of free radicals. You feel rejuvenated with fewer free radicals and more antioxidants, and your cells and tissues are healthier. It can also aid in getting rid of fat deposits.

PureHealth Research has a partnership with Vitamin Angels. Through this, they contribute to providing for undernourished and poor kids with poor diets and no proper means of getting good care. They support them. Thus by buying the Liver Health Formula made by PureHealth, you are also supporting a good cause.

ActivatedYou Morning Complete

Product Overview
Core Ingredients Green Superfood Blend, Metabolic Blend, Liver Supporting Blend, Adaptogens, etc.
Servings Per Container 30
Side Effects No side effects were reported.
Price $79.00

ActivatedYou Morning Complete is a 100% vegan, dairy-free, and artificial sweetener-free supplement. This is an excellent option for anyone in the market for vegan liver detox supplements that can help with proper liver function.

This supplement is not only made for your liver health, but instead, it is a complete dietary supplement. It is packed with prebiotics and probiotics, which promote gut health and are great for digestion.

Consuming this supplement to start your day is a great way to power up your body’s natural functions. This supplement contains a unique mix of 8 different blends. This included a sugar support blend, green superfood blend, metabolic blend, liver support blend, prebiotic fiber blend, adaptogen blend, antioxidant blend, and probiotic blend.

All these are made using high-quality and naturally available ingredients that enable you to get various health benefits to start your day the right way. All you need to do is take one scoop of this green and vegan blend, mix it with one glass of water, and give yourself a glass of goodness.

VitaPost Liver Support Plus

Product Overview
Core Ingredients Artichoke extract, Dandelion root, beetroot extract, etc.
Servings Per Container 30
Side Effects No side effects were reported.
Price $23.95

The VitaPost Liver Support Plus is one of the best liver detox supplements made by the famous VitaPost brand. It combines the usual ingredients such as artichoke leaf and milk thistle with other unique elements such as chicory root and yarrow for added benefits.

Your liver serves as a filter for your blood, cleaning it of impurities and cleansing it. Additionally, it aids in the breakdown of hormones and lipids. Your liver plays several important and varied responsibilities for your health. This supplement by VitaPost helps in all these liver functions and provides additional antioxidant support.

PhytAge Labs Urgent Liver 911

Product Overview
Core Ingredients Silymarin, Curcumin, Yarrow Flower, etc.
Servings Per Container 30
Side Effects No side effects were reported.
Price $69.95

The last supplement for healthy liver function and overall health is PhytAge Labs Urgent Liver 911. PhytAgle Labs are very well known in the dietary supplements industry, thanks to their high-quality products.

The Urgent Liver 911 is full of the goodness of artichoke leaf extract, dandelion root extract, and other healthy natural ingredients. All of which have a significant effect on your liver. It makes it easier for your liver to function and carry out its essential processes.

Bonus Guide The Non alcoholic Fatty Liver Disease Solution


In addition to the liver detox and cleanse supplements, we have included The Non-alcoholic Fatty Liver Disease Solution. This digital guide created by Julissa Clay is excellent for helping with non-alcoholic fatty liver disease.

This digital guide is not a detox formula but a straightforward guide and solution for helping people with Nonalcoholic Fatty Liver Disease. It has information on how to support and maintain a healthy liver and a healthy diet to help with liver health and liver cleanse.

Why Is Liver Health Important?

Our liver is a crucial part of the digestive system and our whole body. One of its primary functions is the production of bile juice. Bile is essential for digestion; poor bile production can harm digestion.

The liver also helps you protect against toxic substances. This is why supporting liver health is essential. Lack of care or viral infections can lead to inflammation of the liver. This is nothing about hepatitis.

Chronic liver diseases such as hepatitis B and C can lead to adverse problems for other parts of your body and other systems such as the immune system.

Scientific Evidence Behind Liver Detox Supplements

There has been a lot of research about liver detox supplements and how they can promote liver health, provide healthy liver function and protect liver cells.

Most liver detox supplements use ingredients such as milk thistle, dandelion root, and artichoke leaf extract.

This study that tested the effects of milk thistle on patients with chronic liver diseases concluded that milk thistle in the form to extract could be used safely to help people with liver-related issues.

Another study looked into the use of artichoke leaf for helping people who suffered from non-alcoholic fatty liver disease and found the results promising. Using artichoke leaf can also help get rid of toxins and free radicals.

Similarly, this 2020 test study that looked into the effects of dandelion root on mice studied how it can help with inflammation, liver fibrosis, and oxidative stress. The study found it to help assist with these issues.

The use of milk thistle in helping with inflammatory liver diseases such as hepatitis B, which causes liver damage and harms liver enzymes, has also been under study. So far, the results haven’t been very concrete, but they have noticed no adverse or harmful effects of milk thistle.

Other ingredients in these liver supplements can also help with immune function and other bodily processes. They can also protect liver cells from unwanted toxins.

Zinc is another common ingredient in these supplements. Although most people know it as an immune booster, zinc is often used in the industry. Chronic liver illness sufferers frequently struggle to have adequate zinc in their bodies to prevent malnutrition. Daily use of zinc can lower the possibility of oxidative damage.

Licorice root is another frequently used significant component in many formulations. According to a 2012 study, using licorice root to treat chronic hepatitis C patients significantly improved their symptoms. Different research assisted in reducing inflammation and weight gain in rats. Although licorice extract may be helpful, excessive consumption might harm the body.

Because it lowers inflammation and keeps joint discomfort at bay, turmeric has earned a distinct position in liver-supporting supplements. But because it can enhance liver health and lessen the effects of hepatic diseases, it is particularly advantageous to the liver.

What Is A Good Quality Liver Supplement?

A good quality liver supplement will contain ingredients that have been clinically tested and proven safe for use. They should be free from any harmful chemicals or additives. Also, they should not contain fillers, binders, preservatives, artificial colors, flavors, sweeteners, or other substances.

Liver health supplements are a great way to help your liver stay healthy and strong. The liver is one of the most critical organs in our body, as it plays an essential role in detoxification, metabolism, digestion, blood clotting, immune system function, and more.

It’s also responsible for producing bile and helping us absorb food’s nutrients. If you want to keep your liver healthy, you need to take care of it properly by eating right, exercising regularly, and taking some good quality liver health supplements.

The best liver health supplements contain natural ingredients like vitamins, minerals, herbs, amino acids, enzymes, antioxidants, and more. These ingredients work synergistically together to give your liver the support it needs to perform its functions effectively.

How Do You Know Which Is The Best Liver Supplement For You?

There are many different types of liver health supplements available on the market today. However, only a few do what they claim to do. So how can you know which ones are worth buying? Here are a few things you should look out for when choosing a liver health supplement:

  • Ingredients: Look at the list of ingredients carefully before making a purchase. Make sure that the product contains only natural ingredients. This includes vitamins, minerals, amino acids, enzymes, and antioxidants. Avoid products with synthetic ingredients such as fillers, binders, and preservatives. These may cause side effects.
  • Dosage: You should always check the recommended dosage of each ingredient included in the product. Some manufacturers recommend higher doses than others. Check the label and ensure you don’t exceed the recommended daily dose.
  • Side Effects: Always read the labels thoroughly before using any new product. Pay attention to any warnings about possible side effects. Ask yourself if the benefits outweigh the risks.
  • Price: Don’t spend too much money on a liver health supplement. There are plenty of affordable options available online and in local stores. See how long their experience has lasted. Does the customer service department respond to questions? Are there any complaints filed against the company?
  • Brand Reputation: Look up the manufacturer on the internet. Find out whether they offer a guarantee and return policy. What kind of refund policies do they have? Do they stand behind their products?
  • Product Guarantee: Most companies provide a 30-day money-back guarantee. If you aren’t satisfied with the results after using the product, you can get your money back.
  • Shipping Policy: How fast does the company ship its orders? How quickly do they deliver them to customers? Can you pick up your order in person?
  • Customer Service: How responsive is the customer service department? Do they answer emails promptly? Do they reply to messages within 24 hours?

How We Ranked The Best Liver Health Supplements?

We used a list of ranking factors to rank the best liver health supplements that can help provide you with normal liver function.

Only liver supplements that lived up to these different factors were included.


The best liver health detox supplements or products should only use the best ingredients. We made sure to take a close look at the elements that make up these supplements.

We also considered additional ingredients besides the usual milk thistle extract and artichoke leaf used in these supplements to protect liver health and cells.

Claimed Health Benefits

Many of these liver detox supplements make bold claims, such as curing or treating liver damage and providing you with improved immune function, and more.

But many of these supplements do not live up to these claims. This is why only the supplements that had the reviews, research, and testing to back their claims were included on this list.

Brand Reputation

We looked at the best brands to find the best liver detox supplements. When you buy anything, you are buying into a brand; hence, the brands with a good reputation through their high-quality products and loyal consumer base were included on this list.


Another essential factor when picking the best liver detox supplements was the price point and the value for money. We have included relatively affordable supplements that avoid the best value for money and the best discounts.

Money-Back Guarantee

Lastly, we also looked at the money-back guarantee offered by these best liver detox supplements. A money-back guarantee makes it easier for consumers to test new products without worrying about losing money.

The Top Liver Supplements in 2022 Final Verdict

That’s all for this article. We recommend you check out these best liver detox supplements to maintain good liver health. These liver supplements can make it easier for you to take care of your liver and prevent chronic issues in the future.

Make sure to follow the dosage instructions carefully and consume a healthy diet in addition to these supplements for maximum benefits.

People with pre-existing medical conditions or medications should avoid these supplements. Don’t forget to consult with your healthcare provider before consuming these supplements.